Lionheart's KLOTHO-UP Study tests supplements to extend healthy ageing

Lionheart Health has launched the KLOTHO-UPTM Study, a clinical trial focused on extending healthspan through advanced supplementation and technology. The programme now includes Rejuvant's CaAKG supplement as a key requirement for all participants. This follows a new partnership between the two companies under the XPRIZE Healthspan initiative.

The study combines Rejuvant's calcium alpha-ketoglutarate (CaAKG) supplement with Lionheart's BodStimTM platform. Participants receive personalised Klotho-focused supplements alongside regular health monitoring. Testing takes place at the start and at set intervals over a 12-month period.

The collaboration brings together Rejuvant's research-backed nutritional products and Lionheart's digital health tools. Both aim to slow ageing and improve long-term health outcomes. CaAKG has now become a mandatory part of Lionheart's Klotho Wellness Program as well.

The KLOTHO-UPTM Study marks a structured effort to merge science-backed supplements with digital health tracking. Participants will undergo regular assessments to measure progress over the year. For the latest details on enrollment or criteria, official study sources remain the only reliable reference.